Gene MSH5

All Male only Female only
Location (GRCh37):
chr6:31,707,725-31,732,622
Description:
mutS homolog 5 [Source:HGNC Symbol;Acc:7328]
Biotype
Protein coding
Nb components:
16
Ensembl:
ENSG00000204410
HGNC Symbol:
7328
MIM gene:
603382
Uniprot:
O43196, H0YDS7, A2ABE9, A2ABF1, Q5SSR2, H7C572, H7C5D6, H7C2J4, A0A494C0L0
WikiGene:
4439
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value