Gene MAN2A2

All Male only Female only
Location (GRCh37):
chr15:91,445,448-91,465,814
Description:
mannosidase, alpha, class 2A, member 2 [Source:HGNC Symbol;Acc:6825]
Biotype
Protein coding
Nb components:
17
Ensembl:
ENSG00000196547
HGNC Symbol:
6825
MIM gene:
600988
Uniprot:
P49641, H0YNG5, A0A0C4DGL1, H0YKH9, H0YLL4, H0YLU3, H0YML7, H0YL67, H0YMU0, H0YKT0, H0YKM7, H0YKQ2, H0YLB9, H0YNC8, H0YK77
WikiGene:
4122
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value