Gene SHC4

All Male only Female only
Location (GRCh37):
chr15:49,115,932-49,255,641
Description:
SHC (Src homology 2 domain containing) family, member 4 [Source:HGNC Symbol;Acc:16743]
Biotype
Protein coding
Nb components:
53 (40 used ?)
Ensembl:
ENSG00000185634
HGNC Symbol:
16743
Uniprot:
Q6S5L8, H0YLZ2, H0YLU6, F5H5M1
WikiGene:
399694
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

Loading

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading