Gene TUBB6

All Male only Female only
Location (GRCh37):
chr18:12,307,668-12,344,319
Description:
tubulin, beta 6 class V [Source:HGNC Symbol;Acc:20776]
Biotype
Protein coding
Nb components:
12
Ensembl:
ENSG00000176014
HGNC Symbol:
20776
MIM gene:
615103
Uniprot:
Q9BUF5, K7ERA8, K7EJZ4, K7EK43, K7EL29, K7EJ64, K7ESQ3, K7EQT3, K7ESM5, K7EPE5, K7EN98, K7ES63
WikiGene:
84617
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value