Gene KMT2A

All Male only Female only
Location (GRCh37):
chr11:118,307,205-118,397,539
Description:
lysine (K)-specific methyltransferase 2A [Source:HGNC Symbol;Acc:7132]
Biotype
Protein coding
Nb components:
17
Ensembl:
ENSG00000118058
HGNC Symbol:
7132
MIM gene:
159555
MIM disease:
159555, 605130
Uniprot:
Q03164, H0YEU4, H7C5W4, A0A3B3ITT0, A0A3B3ITZ6, H7C5V8, A0A3B3ITT7, A0A3B3ISN4, E9PR05
WikiGene:
4297
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

Loading

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading