Gene PTPRC

All Male only Female only
Location (GRCh37):
chr1:198,607,801-198,726,545
Description:
protein tyrosine phosphatase, receptor type, C [Source:HGNC Symbol;Acc:9666]
Biotype
Protein coding
Nb components:
27
Ensembl:
ENSG00000081237
HGNC Symbol:
9666
MIM gene:
151460
MIM disease:
126200, 608971
Uniprot:
P08575, A0A075B788, M3ZCP1, M9MMK8, E9PKH0, A0A2R8YE81, A0A2R8Y5B1, M9MML4, M9MMK9, M9MML3
WikiGene:
5788
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value