Gene TG

All Male only Female only
Location (GRCh37):
chr8:133,879,203-134,147,147
Description:
thyroglobulin [Source:HGNC Symbol;Acc:11764]
Biotype
Protein coding
Nb components:
69 (40 used ?)
Ensembl:
ENSG00000042832
HGNC Symbol:
11764
MIM gene:
188450
MIM disease:
274700, 608175
Uniprot:
P01266, H0YB42, H0YBL4, H0YBC5, E5RG33, H0YBJ2, H0YBQ6, E7EVM0, H0YBR7, H0YBY1
WikiGene:
7038
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

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This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
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