Gene MAP2K2

All Male only Female only
Location (GRCh37):
chr19:4,090,319-4,124,126
Description:
mitogen-activated protein kinase kinase 2 [Source:HGNC Symbol;Acc:6842]
Biotype
Protein coding
Nb components:
22
Ensembl:
ENSG00000126934
HGNC Symbol:
6842
MIM gene:
601263
MIM disease:
615280
Uniprot:
P36507, G5E9C7, M0R1B6
WikiGene:
5605
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value

* Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value